Spermatozoal motion parameters, In vitro storage and processing of animal semen is represents a risk factor to spermatozoa vitality, potentially leading to reduced fertility. Besides applicable outputs, the project outcomes shall serve as a baseline for the creation of high quality publications, education of new generations of scientists and an increased public attention towards science and innovation. In groups V1, V2, T and Sh, the left renal vein was partially ligated to induce varicocele. seemed to protect spermatozoa against the damage caused by the hostile in vitro culture, ... Curcumin posses potent antioxidant properties, it potentiated the antioxidant system through activation of enzymatic and non-enzymatic antioxidants, and inhibition of pro-oxidants production (4). The results indicate that curcumin can significantly improve sperm motility from the patients with leucocytospermia. Hence, increased production of reactive oxygen species (ROS) caused by oxidative stress leads to lipid peroxidation (LPO), apoptosis, and DNA damage. Samples with 300 μM curcumin had the highest amount of plasma membrane integrity and lowest amount of abnormality compared to other treatments and the control group (P< 0.05). In the second experiment when animals were treated with highest concentration of cyclophosphamide, significant increase in the percentage of abnormal sperms was noted .However when animals were primedwith curcumin prior to cyclophosphamide treatment, the cells showed inhibition in the percentage of abnormal sperms. These indicators of oxidative stress can react with polyunsaturated fatty acids (PUFA), resulting in lipid peroxidation in the sperm membrane . In order to verify this hypothesis, we treated mouse spermatids in vitro by histone acetylase (HAT) inhibitor Curcumin. However, some studies suggest that turmeric has benefits, and it's possible that it has benefits that curcumin alone doesn't, but more research on this is needed. Bagdara Farms Health System respects your privacy and contact information will NOT be shared or sold to any third parties under any circumstances. Password requirements: 6 to 30 characters long; ASCII characters only (characters found on a standard US keyboard); must contain at least 4 different symbols; In case of reptiles, no standardized protocol exists to date with respect to the storage or cryopreservation of male gametes. Canine seminal plasma contains antioxidant enzymes to protect sperm against internally generated ROS. e agents with antimicrobial, antioxidant and chemotherapeutic properties. The aim of this study was to evaluate the effects of curcumin on sperm count, motility and viability, semen total antioxidant capacity and DNA integrity of rat spermatozoa during semen freeze-thawing process. Curcumin is a phytochemical that is laden with antioxidant, anti-inflammatory, anti-microbial and testosterone-boosting properties that are very effective in averting male infertility. Whatthis does in men is cause lowered testosterone, enlarged breasts, increased body fat, depression, loss of libido and andropause...all symptoms which were basically unheard of fifty years ago. Spermatozoa motion parameters were assessed using the SpermVision™ computer-aided sperm analysis (CASA) system. , 7, 8, 9, 10 The effect of various doses of curcumin on the spermatozoa superoxide production at 0h, 2h, 6h 12h and 24h. Mexamin-S4 and offering by Bagdara Farms are one of those few choicest supplements that boasts of high-quality curcumin. This spice is a relative of curcumin and cardamon, which all belong to the same plant family. 6) Curcumin. Motility, viability and DNA integrity of sperm were significantly preserved in treatment groups compared to the control (p < 0.05) after freezing-thawing. Since curcumin has become such a huge sensation in the fitness world today, there are many curcumin supplements available in the market. Sperm Morphology – The physical features of sperm are also important when it comes to sperm health. According to RAPD, highest genetic similarity (92%) was between SKI 336 and SKI 343. Conclusion(s): Curcumin has an ameliorative effect on sperm parameters and improves morphologic features of sperm in mice. draw on the basis of subsequent analyses: semen quality assessment, biochemical analyses (SOD activity, MDA level) of semen and micro- and macronutrients content (Ca, Cu, Fe, K, Mg, Na and Zn) assessment in semen, as well. Figure 2B shows that sperm motility significantly (p 0.043) decreased in CFLs group compared to the control group. It reduces sperm motility, viability, and ultimately reduces fertility. Despite years of intensive investigations, still more work should be done in order to perform successful cryopreservation of poultry sperm. The freezing/thawing process can cause some morphological and functional changes via ice crystallization and osmolality imbalance. Objective: Reversing Low Sperm Count and Male Infertility With Curcumin, Drink alcohol to celebrate, Drink Alchorid to celebrate Life, SPICE UP YOUR IMMUNITY & BRACE YOURSELF with curcumin. Dexamethasone induced spermatogenesis defects including epithelial vacuolizations, sloughing of germ cells, reduction of seminiferous tubule diameter, reduction in the number of sperm heads and significant maturation arrest (p < 0.001). Seminal analysis and serum levels of testosterone (T), luteinizing hormone (LH), follicle stimulating hormone (FSH) thyroid-stimulating hormone (TSH), Triiodothyronine (T3), Thyroxine (T4) as well as biological profile and anthropometric measurements in obese men evaluated before and after six-month weight loss programme as compared with baseline and reference range. According to CASA, the best post-thawing sperm motility rate was recorded when the freezing extender was supplemented with 2.5mM curcumin. Oxidative stress occurs when oxidants are more potent than antioxidants. Curcumin and the curcuminoids are present in turmeric at around 22.21-40.36mg/g in the rhizomes and 1.94mg/g in the tuberous roots, so turmeric is less potent as a source of curcumin than an extract and anti-inflammatory. The antioxidants also did not show any effectiveness in the elimination of malondialdehyde (MDA) formation and the maintenance of glutathione peroxidase (GSH-PX) activity, when compared to the controls. Sperm parameters including total sperm count, morphology, motility, progressive motility, sperm concentration and DNA integrity in addition to TAC were evaluated in fresh and frozen-thawed semen samples. Sperm Count – The amount of sperm generated in semen is a good measure of reproductive health. Materials and methods: The anti-inflammatory properties of curcumin are potent enough to reduce the activity of pro-inflammatory enzymes and chemicals like COX-2, cytokines, etc. Friends, your patients will be in good hands with our expert teams. Concentrations ≥50 μmol/L FeCl2 and ≥100 μmol/L FeCl3 led to a significant decrease of spermatozoa motility (P < 0.05) and mitochondrial activity (P < 0.001 with respect to 200-1000 μmol/L FeCl2/FeCl3; P < 0.01 in case of 100 μmol/L FeCl2/FeCl3), accompanied by a significant superoxide overproduction (P < 0.001 in terms of 200-1000 μmol/L FeCl2 and 500-1000 μmol/L FeCl3; P < 0.01 with respect to 100 μmol/L FeCl2 and 100-200 μmol/L FeCl3). Works better with curcumin. This indirectly supports that curcumin significantly ameliorates aflatoxin-induced toxicity in sperm parameters. The aim of this study was to evaluate the effects of curcumin on sperm count, motility and viability, semen total antioxidant capacity and DNA integrity of rat spermatozoa during semen freeze-thawing process. Ultimate Clinical Potency Curcumin - Natural pain relief, reduce inflammation and so much more. For one-third of these couples, the problem lies with the male partner. Several numbers of studies have established the effectiveness of antioxidants like curcumin against oxidative stress. The study was carried out on varicocele-induced rats, and it showed how by scavenging free radicals,  curcumin could reduce the nitric oxide level and increase sperm count. Made using curcumin that is grown at Bagdara Farms, Mexamin-S4 has no chemical residues since the farming techniques used at Bagdara are 100% natural and organic. The involvement of reactive oxygen species (ROS) in physiological cellular processes, as well as in cancer initiation and progression is a highly established topic in current biological research. During sperm cryopreservation, it is exposed to cold and osmotic shock, and resulted in increasing oxidation due to raise in oxidative reactions. Sperm collected from 10 adult rats were divided into two groups (n=10 for each group): control and a test group supplemented with 2.5 mM curcumin. Healthier sperm. All rights reserved. Curcumin is known as an effective antioxidant against oxidative stress. , 7, 8, 9, 10 The effect of various doses of curcumin on the spermatozoa superoxide production at 0h, 2h, 6h 12h and 24h. Effect of curcumin on the total sperm, sperm motility, sperm … Genetic data analysis. Infertility is the disability of a sexually active, non-contracepting couple to achieve pregnancy and reproduce. Cell viability was examined with the metabolic activity 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and the nitroblue-tetrazolium (NBT) test was applied to quantify the intracellular superoxide formation. Use of tumeric and curcumin to alleviate adverse reproductive outcomes of, http://dx.doi.org/10.1002/j.1939-4640.2003.tb031. Sperm collected from 10 adult rats were divided into two groups (n=10 for each group): control and a test group supplemented … SREEJAYAN, J.D., RAO, M.N. Modern chemotherapeutic strategies suggest the feasibility of redox intervention by modulating the ROS generation using novel natural pro- and antioxidant redox chemotherapeutics as well as trace elements that target key signalling pathways, directly regulated by ROS. Too much stress for a prolonged period has an adverse effect on male fertility. For example, Angelicakeiskei powder and Astragalus mongholicus extract showed anti-infertility efficacies in males and females, respectively. The purpose of this study was to determine the effect of epicatechin (EPI) on the motility, viability, and reactive oxygen species (ROS) production of bovine spermatozoa in the presence of various EPI doses during different time periods (Time 0 h, 2 h, 6 h, 24 h). A variety of substances isolated from natural sources may exhibit protective or antioxidant properties on the spermatozoon, thus extending the lifespan of stored ejaculates. SALAHSHOOR, M.R., JALILI, C., KHAZAEI, M.. curcumin on reproductive parameters in male mice. Spermatozoa motility was determined using the HTM IVOS and CASA (Computer Assisted Semen Analyzer) system. Freezing extenders with antioxidants at three different doses led to lower percentages of acrosome and total sperm abnormalities, when compared to the controls (P < 0.001). Since the use of curcumin prevents the formation of ROSs during freezing, it therefore improves the normal morphology of sperm after thawing. The diluted semen was slowly (at a rate of 0.2-0.3°C/min) cooled to 5 °C and then cryopreserved in 0.25mL French straws. Exercising regularly, eating a well-balanced, antioxidant-rich diet, avoiding ill-fitting underwear and prolonged hot water baths and keeping your weight in check are all natural ways to safeguard your fertility. All applied LYC concentrations significantly reduced the intracellular superoxide production, particularly at Times 12h (P<0.01 in the case of 1000 and 2000 μM/L LYC; P<0.05 with respect to 1-500 μM/L LYC) and 24h (P<0.001 in the case of 1000 and 2000 μM/L LYC; P<0.01 with respect to 500 μM/L LYC; P<0.05 given 1-200 μM/L LYC). After curcumin treatment, the level of the H 2 O 2 was significantly decreased in the supernatant of curcumin‐incubated spermatozoa from leucocytospermic patients. Forty-five semen samples were collected from adult breeding bulls and diluted in physiological saline solution supplemented with different concentrations (0, The aim of this study was to assess the dose- and time dependent in vitro effects of resveratrol (RES), a natural polyphenol and phytoalexin with potential antiviral, anti-inflammatory and antioxidant properties on bovine spermatozoa during five different time periods (0h, 2h, 6h, 12h and 24h). These enzymes are removed from seminal plasma during the process of cryopreservation. Context: oxygen species in the pathophysiology of human reproduction. The pooled semen samples were diluted in a Tris-based extender, including curcumin (2.5, 5 or 10 mM), inositol (2.5, 5 or 10 mM), carnitine (2.5, 5 or 10mM) and no antioxidant (control). We supposed the regulation of histone acetylation played an important role throughout this "erasure" process. Cell viability was measured using the metabolic activity MTT assay, and the nitroblue-tetrazolium (NBT) test was used to assess the intracellular superoxide formation. Rank: 7 – It is a very effective ingredient, but I do not suggest that you run out and buy it. The present study aimed to investigate the effects and the mechanisms of various natural products on infertility. 21-24 Curcumin is reported to protect male reproductive system in chromium-induced oxidative damage. A substantial portion of the project is dedicated to study new molecular markers of semen quality in mammals, birds and reptiles, and to the standardization of techniques for their effective and routine assessment. sperm morphology after the freeze-thawing process. http://dx.doi.org/10.1111/j.2042-7158.1997.tb0, http://dx.doi.org/10.1016/j.fertnstert.2007.1, Microsatellite analysis of population structure in Cana, Vienne D.D., ed., Science Publishers Inc., Plymout, WEIR, B.S. © 2021. www.bagdarafarms.com. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. Higher concentrations of EPI (100 and 200 μM/L) also showed significant changes (P < 0.01) in values of viability and ROS production. (x.117) Vitamin E (x.32) Research shows vitamin E is important for fertility. The results indicate that the Chlamydomonas extract is capable of delaying the damage inflicted to the spermatozoon by the in vitro environment. The study was carried out on varicocele-induced rats, and it showed how by scavenging free radicals, curcumin could reduce the nitric oxide level and increase sperm count. One of the most critical milestones in a couple’s life is when they decide to start a family. The samples were cultured at room temperature (22, Motility and progressive motility analysis was, physiological saline solution containing, superoxide formation. Group receiving 200 μM of curcumin had better performances in terms of VAP, VSL, VCL, and LIN. The Effect of Adding Different Levels of Curcumin and Its Nanoparticles to Extender on Post-Thaw Quality of Cryopreserved Rabbit Sperm. Out of three groups, group I had fifteen genotypes while rest of the genotypes were divided among two groups. Rosemary Nutrition. The effect of curcumin on sperm parameters is controversial. 1994. Asterisk (*) within a bar graph indicates significant difference between the means (P < 0.05). The complete genetic makeup or genotype of an individual is represented by its entire DNA sequence; however, until entire genomes can be sequenced with little effort, geneticists will continue to rely on genetic markers as a means of characterising the genotypic variation of individuals. 16. Semen samples were cultivated in physiological saline solution containing 200, 100, 50, 10, 5 and 1 μM/L of EPI dissolved in 0.5% DMSO. TAC was significantly higher in 2.50 mM group than other groups. By promoting healthy liver function, curcumin helps improve the body’s metabolism and thus ensures that the fat burning ability of the body is intact. Semen samples were collected from 20 adult breeding bulls, and diluted in physiological saline solution containing 0.5% DMSO together with 0, 1, 5, 10, 50 and 100 μM/L of curcumin. Curcumin is among the best-researched natural anti-inflammatory compounds. In conclusion, curcumin seems to emolliate sperm parameters and to protect sperm against sperm reactive oxygen stress and increases NOX5 gene expression. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Cell viability was examined using the metabolic activity MTT assay and the nitroblue-tetrazolium (NBT) test was applied to quantify the intracellular superoxide formation. The remaining eight (experimental) groups were supplemented with 5, 10, 25 or 50 mol/L CUR (Sigma-Aldrich) in the presence or absence of FeAA. Gene ID: 3717, updated on 3-Feb-2021. Effect of curcumin on the total sperm, sperm motility, sperm mortality and testicular weight The one-way ANOVA showed that the total sperm in the curcumin group had no significant change compared to CFLs and control groups (Figure 2A). This project was concieved to develop novel as well as to innovate currently available methods and protocols used for a more effective preservation of animal ejaculates at low temperatures. The conclusions will be. ... you can mix powdered ashwagandha with turmeric curcumin, Boswellia, or ginger extract. The cell viability was measured by the MTT (metabolic activity) assay and chemiluminescence was evaluated to quantify the ROS generation. In a direct comparison, divalent iron has been shown to be more toxic than trivalent iron. Morphological trait analysis and statistical analysis of markers were useful for reconstructing a castor varietal dendrogram. 1990. Results and discussion: The freezing extender supplemented with 200 μM of curcumin resulted in higher percentages of total and progressive motilities in comparison with other groups and control group following the freeze-thawing process (P <0.05). 2013;41(6):1555-1564. If you too would like to start a family but have been grappling with reproductive issues, then go ahead and order a jar of Mexamin-S4. There was no increase in the percentage of abnormal sperms in curcumin treated groups when compared with control values. Thirty male Wistar rats were randomly divided into 5 groups (V1 and V2 (varicocele), T (treatment), Sh (sham) and C was control). Moreover, unique morphological and metabolic features of avian spermatozoa represent a significant challenge for the standardization of methodologies related to the processing and preservation of male genetic material. Stimulating and protective effects of vitamin E on bovine spermatozoa, Characterization of castor (Ricinus communis L.) genotypes using different markers, Effect of curcumin on rat sperm morphology after the freeze-thawing process, Histone Acetylase Inhibitor Curcumin Impairs Mouse Spermiogenesis–An In Vitro Study, Effect of curcumin on dexamethasone-induced testicular toxicity in mice, Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes, Comparison of different evaluation chambers for analysis of rabbit spermatozoa motility parameters using CASA system, Protective effects of curcumin in cyclophosphamide induced sperm head abnormalities in male mice, APVV-15-0543 - Analysis of the modulatory effects of biologically active substances on the physiological and pathological oxidative processes in cell models, Investigating the influence of different doses of taurine on semen characteristic in New Zealand White rabbit treated with mercury in vitro. This ensures that taking Mexamin-S4 regularly will not cause any untoward side-effects. Spermatozoa motion parameters were determined using the SpermVisionTM and CASA (Computer Assisted Semen Analyzer) system. Effect of curcumin on dexamethasone-induced testicular toxicity in mice Layasadat Khorsandi, Mehri Mirhoseini, Masoomeh Mohamadpour, Mahmoud Orazizadeh, and Soheila Khaghani Cell & Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran abstract Context: Curcumin is a yellow-orange polyphenol derived from turmeric [Curcuma longa L. … Curcumin has a potent protective effect against the testicular toxicity and might be clinically useful. © 2008-2021 ResearchGate GmbH. Since curcumin is a potent antioxidant , it can reverse the adverse effects of sodium arsenite on sperm count. An integrated approach based on the exploitation of morphological traits and molecular markers, such as RAPD and ISSR fingerprints was employed. Expression of Bcl-2 was significantly increased in the curcumin + dexamethasone group compared with dexamethasone-treated animals (p < 0.05). The obtained results indicated that HAPNPs caused a significant decrease in sperm count, sperm motility, testosterone hormone, steroidogenic enzymes (17-ketosteroid reductase and 17β-hydroxysteroid dehydrogenase), and antioxidant enzymes (glutathione peroxidase, glutathione S-transferase, catalase, and superoxide dismutase) in addition to total antioxidant capacity and reduced … A shocking study published in a journal called Human Reproduction Update suggested that the average male sperm count has slid by more than 50% in the 40 years that have passed. The results indicate that lycopene may enhance spermatozoal activity and protect against cellular deterioration resulting from exposure to the in vitro environment. Analysis of the effect of nicotine, curcumin and curcumin-nicotine on sperm motility (A), sperm count (B) and sperm normal morphology (C). Motility after 2 h of cultivation showed significant increase (P < 0.05) values only at concentration 100 μM/L. Scientists in Peru wanted to see what would happen if they combined black maca root and camu camu fruit. Curcumin is known as an effective antioxidant against oxidative stress. While considerable number of studies has strongly revealed an energy-promoting and protective effects of curcumin on sperm parameters [23]. Therefore we have hypothesized that sodium arseniteinduced oxidative stress might be responsible for reductions in sperm count. S., AKALIN, P.P., BUYUKLEBLEBICI, S., KUCUKGUNAY, S. 2. of curcumin and dithioerythritol on frozen-thawed bovine semen. The project focuses on the improvement of the quality as well as the possibilities to preserve and freeze spermatozoa, and to ensure post-cryopreservation semen samples of high quality in veterinary and breeding practice. Semen samples were collected from 20 adult breeding bulls, and diluted in physiological saline solution, This study was designed to assess the effects of lycopene (LYC) on motility, viability and superoxide production of bovine spermatozoa during short-term (0h, 2h, 6h) and long-term (12h, 24h) in vitro culture periods. Indeed, our results revealed that curcumin treatment alone had no adverse effect on sperm count, viability, motility, or morphologic structures (see Table 1). Less than fifteen million sperm per ml of semen is considered to fit in the low sperm count bracket. Curcumin is known as an effective antioxidant against oxidative stress. Key Words: Aflatoxin, curcumin, cauda epididymis, spermatozoa, viability, motility ThereportbyCarlsenetal. Curcumin is a yellow-orange polyphenol derived from turmeric [Curcuma longa L. (Zingiberaceaerhizomes)]. 24 h of cultivation confirmed the protective effect of EPI in experimental groups after comparison with the control group with significant differences (P < 0.001) for motility, as well as for viability and ROS production in concentrations ranging between 1 and 50 μM/L. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. The freezing extender supplemented with 2.5mM curcumin led to higher percentage of computerassisted semen analyzer (CASA) sperm motility (65±3%), when compared to the control, inositol and the 10mM carnitine (P < 0.01) groups, following the freeze-thawing process. Curcumin as an indirect methylation inhibitor modulates the effects of Toxoplasma gondii on genes involved in male fertility. Three concentrations were tested 10, 15 &20mg/kg of the curcumin the prepared slides were observed for various types of sperm head abnormalities. Arthritis stems from chronic inflammation of the joints. The aim of this study was to investigate the effects of different levels of curcumin antioxidants (0, 100, 200 and 300 μM) in Beltsville modified diluents for the cryopreservation of rooster semen. Tripterygium glycoside decreased fertility ability both in males and females. Also, consuming a curcumin supplement regularly can go a long way in helping you keep your sperm health intact. Two experiments were conducted to evaluate the protective effects of curcumin against cyclophosphamide induced cytogenetic damage in swiss albino mice, in the first experiment the antigenotoxic effects of curcumin were studied in germ cells of mice. Superoxide dismutase (SOD) activity was found to be higher in the presence of curcumin at all three dose levels and carnitine at 5mM, compared to the other groups. Growing community by inspiring healthy, whole, abundant living. The ameliorative effects of curcumin on MTZ induced toxicity on mice spermatozoon tail length, count, motility and testosterone level were investigated. Several natural lifestyle choices can help an individual maintain good sperm health. Chronic inflammation that is usually a side effect of drinking too much alcohol is also a reason for low sperm count. Natural dietary antioxidants are extensively studied for their ability to protect cells from damage to DNA induced byheavy metals. Men may also notice improved sperm count and even enhanced erections. After freezing-thawing, the number of spermatozoa, motility, viability, total antioxidant capacity (TAC), and DNA integrity of the sperm were analyzed. However, administration of curcumin significantly improved the histopathological in testis, increased the sperm count, motility, viability, and also significantly increased the SOD, GPx, and decreased MDA in testis of lead acetate-treated rats. Results: Curcumin at 2.50 mM provided a greater protective effect on the DNA integrity compared to 5.00 mM and control groups. The lower quality of frozen-thawed poultry sperm and consequently the poor fertilization rates compared to mammalian species are due to the exceptional morphological properties of poultry sperm, which cause freeze damages because of their vulnerable structure to low temperatures. Material and methods: Semen samples were collected from eight Ross 308 rooster three times a week by massaging along the backbone and abdomen .The criteria in normal quality of sperm was as follows: the volume between 0.2 and 0.6 ml (semen volume was measured visually using a graduated collection tube); the concentration of sperm ≥ 3˟109 sperm/ml (ejaculate concentration was evaluated by haemocytometer); total motility ≥80% and abnormal morphology (Hancock method [17]) ≤ 10%. The anti-inflammatory properties of curcumin are potent enough to reduce the activity of pro-inflammatory … In vitro effects of the Chlamydomonas reinhardtii extract on bovine spermatozoa. This gene encodes a non-receptor tyrosine kinase that plays a central role in cytokine and growth factor signalling. Based on our results, it is concluded that curcumin addition during freezing resulted in positive effects on sperm parameters after thawing in adult rats. (1)indicatesthatsemenqualityin men worldwide has undergone a decline over … 1, 5, 10, 50, 100, 200, 500, 1000 μmol/L) of FeCl2 or FeCl3. Thirty-two NMRI mice were randomly divided into 4 groups. Note: Turmeric’s Antifertility effect (poster), As spermatozoa are particularly sensitive towards oxidative damage, the search for a potential antioxidant substance to preserve and protect them under in vitro conditions has recently attracted the attention of the scientific community. Balanced between its use as a flavorful ingredient and as an element of traditional medicine, many people rely on garlic juice for its anti-inflammatory, anti-carcinogenic, antibacterial, anti-fungal and antioxidant effects.Garlic juice is a rich source of allicin, the active ingredient in garlic. Results from this in vitro study show that high concentrations of both forms of iron are toxic, while their low concentrations may have spermatozoa activity-promoting properties. Curcumin reduced an enzyme needed to make PGE2 in blood cells . The results of this study demonstrate that curcumin increases the expression of Bcl-2 protein, an important anti-apoptotic factor, and improves the spermatogenesis defects in dexamethasone treated mice. Protective effect of curcumin on fertility of rats after exposure to compact fluorescent lamps: An experimental study ... total sperm count compared to the control group. Formazan can, www.graphpad.com). In the case of ROS production and even spermatozoa viability after 2 h of cultivation was not observed significant differences. After 6h, the decline, These beneficial effects remained visible and, P<0.05 in case of group D). There is a significant reduction in weight and high improvement semen, hormonal, biological profile and anthropometric measurements as compared to the reference range. Forth group received 200 mg/kg of curcumin for 10 days after dexamethasone treatment. . Contact us today and we’ll make the connection as soon as possible. In groups V1, V2, T and Sh, the left renal vein was partially ligated to induce varicocele. Congenital factors, acquired urogenital abnormalities, urogenital tract infections, endocrine disturbances, genetic abnormalities, immunological factors, obesity and lifestyle factors are among of infertility causes.
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